physician photo

Gwen Hoben, MD

Undergraduate: Rice University (Chemistry)

Medical School: Baylor College of Medicine, 2009

Hometown: San Antonio, Texas

Gwen Hoben

Research Interests

Research and Career Interests: I plan to pursue an academic career in hand and general reconstructive surgery as well as basic science research in nerve regeneration. Next year I am excited to be doing the hand fellowship at the Medical College of Wisconsin.

Selected Publications

Poppler L, Ee X, Schellhardt L, Hoben G, Pan D, Hunter D, Yan Y, Moore A, Snyder-Warwick A, Stewart S, Mackinnon SE, Woor MD. Axonal growth arrests after an increased accumulation of Schwann cells expressing senescence markers and stromal cells in acellular nerve allografts. Tissue Engineering Part A: 2016 (epub June 13, 2016)

Dlouhy B, Nguyen D, Patel K, Hoben G, Skolnick G, Naidoo S, Woo A, Smyth M. Endoscopic assisted management of sagittal synostosis-wide vertex suturectomy and barrel stave osteotomies versus narrow vertex suturectomy. Journal of Pediatric Neurosurgery: 2016 (accepted June 28, 2016)

Farber SJ, Hoben G, Hunter DA, Yan Y, Johnson PJ, Mackinnon SE, Wood MD. Vascularization is delayed in long nerve constructs compared to nerve grafts. Muscle Nerve: 2016 (epub May 3, 2016)

Fox IK, Davidge KM, Novak CB, Hoben G, Kahn LC, Juknis N, Ruvinskaya R, Mackinnon SE. Nerve transfers to restore upper extremity function in cervical spinal cord injury: Update and preliminary outcomes. Plastic and Reconstructive Surgery: 2015, 136(4): 780-92.

Hoben G, Yan Y, Iyer N, Newton P, Hunter D, Moore A, Sakiyama-Elbert S, Wood M, Mackinnon SE. Comparison of acellular nerve allograft modification with Schwann cells or VEGF. HAND: 2015, 10(3), 396-402.

Fox IK, Davidge K, Novak C, Hoben G, Kahn L, Juknis N, Ruvinskaya R, Mackinnon SE. Use of peripheral nerves transfers in tetraplegia: evaluation of feasibility and morbidity. HAND: 2015, 10(1), 60-67.

Hoben G, Moore AM, Wood M, Mackinnon SE. Schwann cell senescence: a new consideration in nerve repair and grafting. American Society for Peripheral Nerve Newsletter: 2013, 3(5), 8-10.

Hoben G, Moore AM, Wood M, Mackinnon SE. Schwann cell senescence: a new consideration in nerve repair and grafting. World Society for Reconstructive Microsurgery Newsletter: 2013, 4(1), 6-7.

Hoben G, Schmidt VJ, Bannasch H, Horch RE. Tissue augmentation with fibrin sealant and cultured fibroblasts: a preliminary study. Aesthetic Plastic Surgery: 2011, 35(6), 1009-15.

Hoben G, Willard V, Athanasiou KA. Fibrochondrogenesis of hESCs: Growth factor combinations and co-cultures. Stem Cells and Development: 2009, 18(20), 283-92.

Hoben G and KA Athanasiou. Use of staurosporine, an actin modifying agent, to enhance fibrochondrocyte matrix gene expression and synthesis. Cell and Tissue Research: 2008, 334(3), 469-76.

Hoben G, Koay EJ, Athanasiou KA. Fibrochondrogenesis in two embryonic stem cell lines: Effects of differentiation timelines. Stem Cells: 2008, 26(2), 422-30.

Hoben G and KA Athanasiou. Creating a spectrum of fibrocartilages through different cell sources and biochemical stimuli. Biotechnology and Bioengineering: 2008, 100(3), 587-598.

Hoben G, Koay EJ, Athanasiou KA. Scaffoldless cartilage tissue engineering with chondrogenically-differentiated human embryonic stem cells. Invention disclosure and patent application, 2007.

Koay EJ, Hoben G, Athanasiou KA. Tissue engineering with chondrogenically-differentiated human embryonic stem cells. Stem Cells: 2007, 25(9), 2183-90. 

Hoben G, James R, Hu J, Athanasiou KA. Self assembly of meniscal fibrochondrocytes for tissue engineering of the knee meniscus. Tissue Engineering: 2007, 13(5), 939-46.

Hoben G, Athanasiou KA. Meniscal repair with fibrocartilage engineering. Biomaterials in Sports Medicine Issue: Sports Medicine and Arthroscopy Review: 2006, 14(3), 129-137.

Vertrees T, Hoben G, Kobylivker A, Edwards C, Bott S, Barron A. Molecular structure of [(tBu)2Al(µ-OC6H4-2-Me)]2. J. Chem. Cryst: 2005, 35, 313.

Hoben G, Huang W, Thoma BS, LeBaron RG, Athanasiou KA. Quantification of varying adhesion levels in chondrocytes using the cytodetacher. Annals of Biomedical Engineering: 2002, 30(5), 703-712.

PRESENTATIONS
Hoben G, Ee X, Schellhardt L, Yan Y, Hunter D, Moore AM, Snyder-Warwick A, Stewart S, Mackinnon SE, Wood M. “A bronze standard: Nerve autografts and Schwann cell senescence.” American Society for Peripheral Nerve, podium presentation: Scottsdale, AZ. 2016

Hoben G, Hunter D, Juknis N, Ruvinskaya R, Novak C, Davidge K, Kahn L, Mackinnon S, Fox IK. “Histomorphometric analysis of recipient nerve tissue in the setting of late nerve transfer after cervical spinal cord injury.” American Society for Peripheral Nerve, podium presentation: Scottsdale, AZ. 2016

Hoben G, Ee X, Prange L, Hunter D, Moore AM, Stewart S, Mackinnon SE, Wood M. Notch signalling in senescent Schwann cells: a target for improving nerve regeneration. Plastic Surgery Research Council, podium presentation: Seattle, WA. 2015

Poppler L, Ee X, Prange L, Hoben G, Hunter D, Yan Y, Stewart S, Mackinnon SE, Wood M. Cellular senescence onset coincides with axonal regeneration arrest in long acellular nerve grafts. Plastic Surgery Research Council, podium presentation: Seattle, WA. 2015

Hoben G, Ee X, Prange L, Hunter D, Moore AM, Stewart S, Mackinnon SE, Wood M. Notch signalling in senescent Schwann cells: a target for improving nerve regeneration. American Association of Plastic Surgeons, podium presentation: Scottsdale, AZ. 2015

Hoben G, Ee X, Moore AM, Wu Y, Newton P, Hunter D, Johnson P, Stewart S, Wood M, Mackinnon SE. “Schwann cell senescence: a key role in reducing axon regeneration.” American Society for Peripheral Nerve, podium presentation: Paradise Island, Bahamas. 2015

Hoben G, Varmun R, James A, Juknis N, Ruvinskaya R, Novak C, Davidge K, Kahn L, Mackinnon S, Fox IK. “Nerve transfers to restore hand function in cervical spinal cord injury: A more appealing and accessible option for patients?” American Society for Peripheral Nerve, podium presentation: Paradise Island, Bahamas. 2015

Hoben G, Yan Y, Iyer N, Newton P, Hunter D, Moore A, Sakiyama-Elbert S, Wood M, Mackinnon SE. “Returning what is lost: Schwann cell versus VEGF addition to acellular nerve allografts.” American Society for Surgery of the Hand, podium presentation: Boston, MA. 2014

Hoben G, Wu Y, Newton P, Ee X, Hunter D, Moore AM, Stewart S, Johnson P, Wood M, Mackinnon SE. “Senescent Schwann cells inhibit nerve regeneration in a short conduit model.” Plastic Surgery Research Council, podium presentation: New York City, NY. 2014

Patel K, Hoben G, Skolnick G, Naidoo S, Smyth M, Woo A. “Endoscopic assisted management of sagittal synostosis: wide vertex suturectomy and barrel stave osteotomies versus narrow vertex suturectomy.” American Society of Plastic Surgeons, podium presentation: San Diego, CA. 2013

Hoben G, Koay EK, Athanasiou KA. “Fibrochondrogenesis in two embryonic stem cell lines: Effects of differentiation timelines.” Biomedical Engineering Society Conference, poster presentation: Los Angeles, CA. 2007

Hoben G, Koay EK, Athanasiou KA. “Fibrochondrogenesis in two embryonic stem cell lines: Effects of differentiation timelines.” Institute of Biosciences and Bioengineering Annual Conference, poster presentation: Houston, TX. 2007

Hoben G, Athanasiou KA. “Fibrocartilage tissue engineering with diverse cell sources,” Hertz Fellowship Symposia, poster presentation: San Jose, CA. 2007

Hoben G, Athanasiou KA. “Fibrocartilage tissue engineering with diverse cell sources,” Keystone Symposia: Tissue Engineering and Development, poster presentation: Snowbird, UT. 2007

Hoben G, Hu J, Athanasiou KA. “Scaffoldless tissue engineering of fibrocartilage using diverse cell sources.” 21st Annual MD/PhD Student Conference, poster presentation: Keystone, CO. 2006

James R, Hoben G, Athanasiou KA. “Short-term effects of passage techniques for articular and meniscal chondrocyte adhesion and aggregation.” Rice-Houston Alliances for Graduate Education and the Professoriate Summer Symposium, Houston, TX. 2005

Hoben G, Hu J, Athanasiou KA “Self assembly of meniscal fibrochondrocytes for tissue engineering of the knee meniscus.” Biomedical Engineering Society Conference, podium presentation: Baltimore, MD. 2005

Möbest D, Jaeger M, Hoben G, Hamann D, Wollner S, Stark GB. “Carbon source has considerable influence on extracellular matrix formation demonstrated by specific collagen expression in primary human tenocytes.” European Society of Animal Cell Culture Technology, Granada, Spain. 2003

Hoben G, Möbest D Stark GB. “Tissue engineering the tendon.” German Fulbright Commission Conference, podium presentation: Berlin, Germany. 2002

BOOK CHAPTERS
Hoben G and Patel K. “Plastic and Reconstructive Surgery.” The Washington Manual of Surgery, 7th ed. Lippincott, Williams, and Wilkins: 2015.

Hoben G and Fox I. “Chest Wall Defect.” Plastic Surgery Case Review: Oral Board Study. Thieme: 2014

Hoben G and Tenenbaum M. “Gynecomastia.” Plastic Surgery Case Review: Oral Board Study. Thieme: 2014

Hoben G and Woo A. “Scalp Burn Reconstruction.” Plastic Surgery Case Review: Oral Board Study. Thieme: 2014

Hoben G and Woo A. “Neck Burn Contracture.” Plastic Surgery Case Review: Oral Board Study. Thieme: 2014